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London (CNN Business)1. China's currency: The yuan hit its lowest level against the US dollar since January 2017 in early trading in Asia, after the Trump administration decided not to label China a currency manipulator.

President Donald Trump promised to designate China currency manipulator during the 2016 campaign.
In the past six months, the yuan has dropped more than 9% against the dollar. And there are signs that the currency may fall further to 7 yuan per dollar — a level not seen since the 2008 financial crisis.
    2. Novartis cancer deal: Novartis (NVS) is buying American cancer drug maker Endocyte (ECYT) for $2.1 billion, the Swiss pharmaceutical giant announced Thursday.
    Endocyte is developing targeted radio therapies, focusing on prostate cancer. Shares in Novartis rose by 1.5% after the announcement.
    Novartis said last month it would cut approximately 2,000 jobs in the next four years to save around $1 billion.
    3. Brexit stalemate: Europe is stepping up preparations for a messy Brexit after yet another meeting between the European Union and the United Kingdom ended in a stalemate.
    European leaders on Wednesday dropped plans for a special November summit to complete a Brexit deal because of a lack of progress in the negotiations.
    British Prime Minister Theresa May offered “nothing new” in a presentation to EU leaders at a critical meeting on Wednesday, according to the head of the European Parliament.
    4. Global market overview: US stock futures were pointing lower early on Thursday.
    European markets were up, while equities in Asia ended the session mostly lower.
    The Dow Jones industrial average closed 0.4% lower on Wednesday, while the S&P 500 and the Nasdaq finished flat.
    US oil futures dropped 0.3% to $69.55 per barrel early on Thursday, after plunging 3% on Wednesday after a report from the Energy Information Administration showed an increase in US inventories of crude.
    5. Companies and economics: Blackstone (BX) and Philip Morris International (PM) plan to release earnings before the open Thursday. American Express (AXP), E*TRADE (ETFC) and PayPal (PYPL) will follow after the close.
      Shares in Air France KLM (AFLYY) shot up more than 6% on Thursday, after French media reported that management and unions are nearing a deal on pay. The airline has struggled with strikes in the past year and shares in the company have dropped by 37% since January.
      6. Coming this week:
      Thursday — American Express (AXP), Blackstone (BX), Bank of New York (BK), E*TRADE (ETFC) and PayPal (PYPL) earnings
      Friday — Procter & Gamble (PG), VF Corp (VFC) and State Street (STT) earnings